Calcium D-GLUCARATE

Calcium D-GLUCARATE
C. Norman Shealy, M.D., Ph.D.

My friend Deena Spear, one of the great healers I know, recently put me in touch with a man who nearly died from a prescribed Fluoroquinolone drug for a urinary tract infection. He had one of the life threatening “side effects”, especially common with Levaquin? and Tequin?. Incidentally, a couple of years ago, within a few days on one of those drugs, I rapidly developed severe hypoglycemia, which took me a year to overcome. Indeed those drugs can CA– USE diabetes as well as severe polyneuropathy and many other serious problems.

I have had some correspondence with the gentleman and learned that he has mostly recovered, using calcium D-glucarate. Glucaric acid is found in small quantities in oranges, apples, grapefruit, cherries and the cruciferous vegetables. The calcium salt of this natural substance inhibits beta-glucuronidase, an enzyme produced in the colon by bacteria there. Elevated beta-glucuronidase activity is associated with significant increased risk of breast, prostate and colon cancers, 3 of the most common!? Interestingly, calcium-D-glucarate also helps regulate estrogen metabolism and lower cholesterol. Thus, gynecomastia reversal in older men, who have impaired regulation of estrogen, is a potential benefit from calcium-D-glucarate (DCG).

Perhaps most importantly, DCG is a major detoxifier of various chemical carcinogens, steroids, and lipid-soluble toxins. It increases excretion of xenobiotic compounds-those foreign substances such as antibiotics, pollutants, dioxin and polychlorinated biphenyl’s, etc. It also enhances intestinal-hepatic circulation. It may be helpful to athletes doing intensive body building, in ridding them of the toxins associated with their metabolism. Considering the pollution of the world with petrochemical pollutants and artificial estrogens, etc, it appears everyone may benefit from calcium D-Glucarate. If you have had antibiotics and have never felt “right” since then, consider taking calcium-D-Glucarate.

The general dose for an adult is 250 mg twice daily. It contains 50 mg of calcium so you receive the recommended 200 mg of D-glucarate. This small amount of calcium is not of concern in those taking large dosages of D 3. In fact it is less calcium than in a good multivitamin/mineral supplement. It is available at http://www.selfhealthsystems.com or 888-242-6105.

Ref:
Biochem Med Metab Biol 1990;43:83-92.
Cancer Detect Prev 1997;21:178-190.
Isr J Med Sci 1995;31:101-105.

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